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Image Search Results
Journal: bioRxiv
Article Title: Amoebicidal Action of Licorice-Derived Compounds: Mechanisms and Effects Against Acanthamoeba castellanii
doi: 10.1101/2025.02.17.638758
Figure Lengend Snippet: Suppressing A. castellanii trophozoites viability by isoliquiritigenin (ISL) and glabridin (GLA). (A, B) Viability of trophozoites following 50 μM and 100 μM licorice derivatives treatments for 24 h determined using the CellTiter-Glo assay. (C, D) Viability of trophozoites following 40-100 μM ISL and 1-64 μM GLA treatments for 24, 48, and 72 h. (E) IC 50 values of ISL and GLA in A. castellanii , HCEC and Caco-2 cells. Data are mean ± SD of n = 3 biological replicates. (F) Morphological changes on trophozoites incubated with control (0.1% DMSO) and different concentration of ISL and GLA for 24 h. Scale bar: 20 μm. (G) Images of trophozoites after 24 h of ISL and GLA treatment with Hoechst 33342 - PI staining. Scale bar: 25 μm.
Article Snippet:
Techniques: Glo Assay, Incubation, Control, Concentration Assay, Staining